Abstract
Introduction: Cumin (Cuminum cyminum L.) is an annual plant that is not only one of the most popular seed species but also one of the oldest and most cultivated aromatic and herbaceous natural products with numerous medicinal, nutraceutical, and pharmaceutical properties. It is widely used in the beverage, food, liquor, medicine, perfume, and toiletry industries. The objective of this work was to provide a precise and up-to-date review of the ethnopharmacology, phytochemistry, and biological activities of cumin.
Methods: Information was gathered from the review of relevant literature obtained from various databases, such as Science Direct, Springer, PubMed, Google, and Google Scholar.
Results: The various parts of the cumin plant (leaves, shoot, root, and flowers) contain similar and different chemical compounds.
Conclusion: The medicinal and health potential of cumin is mainly attributed to its antioxidant, antibacterial, antifungal, anti-inflammatory, antidiabetic, insecticide, and immunomodulatory properties. More studies are, however, required to unravel novel components and applications of cumin.
Introduction
The usage of herbal and other natural products for disease management, whether for prevention or treatment, has been known for ages1, 2, 3, 4, 5. Some edible herbal plant species, such as cumin (Cuminum cyminum L.), are also commonly used as food additives owing to their accessibility, safety, and usefulness6. Cumin belongs to the Apiaceae family, tribe Ammineae, and subtribe Carinae, and has 2n = 14 chromosomes7, 1, 6.
Cumin is the second most popular seed species after black pepper8. It is an annual plant and is also one of the oldest and most cultivated aromatic and herbaceous natural products with numerous medicinal, nutraceutical, and pharmaceutical properties. Cumin also has wide usage in the beverage, food, liquor, medicine, perfume, and toiletry industries7. It is native to and cultivated extensively in several places, mainly in arid and semi-arid climates, such as China, Egypt, Saudi Arabia, and the Mediterranean, as well as India and Iran. However, the largest consumer of cumin seed in the world is India while China is the largest exporter and producer. Cumin has remarkable antioxidant properties and is traditionally used as an astringent, carminative, coagulant and stimulant, as well as remedy against diarrhea, dyspepsia, epilepsy, toothache, whooping cough, flatulence, indigestion, and jaundice9, 7, 6, 10, 11.
Cumin grows to about 30–60 cm tall, with a glabrous, branched, and slender stem. It has compound leaves with thread-like leaflets.
It has terminal umbel inflorescence. Each cumin branch has 3-9 umbels with 5-7 umbellets, consisting of small hermaphrodite flowers which are either white or pink. It has schizocarps, i.e. fruits containing two mericarps, and about 6 mm long seeds which are oblong but thicker in the middle. It is mostly planted in the winter or autumn with the emergence of seedlings occurring after about 14 – 50 days. Cumin seed germination usually occurs at low temperatures (< 20 °C) and is arrested at high temperatures12. Cumin has a weak vigor owing to its increased sensitivity to environmental stresses and because its seeds contain 10% oil11.
The seeds of cumin are characterized by abortifacient, antispasmodic, diuretic, emmenagogic, carminative, and stomachic properties. Oleoresin from the seeds is commonly applied in crackers, sauces, meat, and sausages. The distinct and strong aroma of the seeds are responsible for its use as spices as well as other medicinal uses. The aroma is mainly due to cuminol which makes up 2.5 – 4.0% of the seed. The essential oils of cumin seeds primarily contain hydrocarbons and aldehydes8.
The objective of this work is to provide a precise and up-to-date review of the ethnopharmacology, phytochemistry, and biological activities of cumin. The information was gathered from the review of relevant literature obtained from various databases, such as Science Direct, Springer, PubMed, Google, and Google Scholar.
Previous studies on C. cyminum
According to literature, the quality and quantity of the compounds commonly identified in cumin vary in the various parts of the plant, such as the leaves, shoots, roots, and flowers. Though both the shoots and flowers have relatively similar terpene compounds, their concentrations are higher in the flowers. Furthermore, α-pinene and β-pinene were not found in the roots, α-phellandrene was notably the only detected terpenoid compound in the leaves while the flowers had the highest concentration of α-pinene13.
Cumin fruits mainly contain cellulose, fixed oil content (about 10%), mineral elements, protein, sugar, and volatile oils (1.5%), as well as appreciable amounts of phenolic compounds14. Formulated C. cyminum essential oil in oil-in-water nanoemulsions have demonstrated successful incorporation of lipophilic bioactive agents into functional food gels15. Natural deep eutectic solvents have also been used to significantly enhance cumin essential oil extraction with a higher yield and premium quality, as an eco-friendly and economical extraction technique16.
An increase in enzymatic (amylase, lipase, protease, and phytase) activities and antioxidant activity were achieved with saline and hot aqueous cumin extracts, as well as its oleoresin and essential oil17. Water-soluble C. cyminum polysaccharides possess lower molecular weight and effectively stimulate RAW264.7 and NK-92 cells to express interleukin (IL)-1β, IL-6, IL-12, and tumor necrosis factor (TNF)-α inflammatory cytokine, and release nitric oxide18. Kedia and colleagues have also reported the fumigant, larvicidal, oviposition deterrent, ovicidal, repellent, and pupaecidal activities of C. cyminum seed essential oil, as well as its 4 main components (cymene, cumin aldehyde, γ-terpinene, and (−)-β-pinene) against Callosobruchus chinensis and Sitophilus oryzae19. Cumin is considered a very useful eco-friendly alternative for the management of insect infestation in food commodities. C. cyminum also has a remarkable antibiofilm and quorum sensing inhibitory potential against Gram-negative bacterial pathogens20. The essential oils of cumin have also demonstrated strong fumigant effects and toxicity against Anopheles gambiae 21.
E thnopharmacology of Cumin
The common ethnomedicinal uses of cumin are summarized in Table 1. Traditionally, cumin is commonly used as a remedy against gastrointestinal, inflammatory and neurological disorders, as well as toothaches21. In Iranian traditional medicine, cumin fruits are also used as a medication for colic, diarrhea, dyspepsia and flatulence, and for stimulation of breast milk production14. It is used in Morocco for the flavoring of foods and soft dates10. It is also commonly used in Tunisia as aromatic herbs and culinary spices6, as well as in Italy for various gastrointestinal and neurological diseases21.
Region | Plant part used | Traditional uses and ethnobotanical reports | References |
Iran | Spice | Antispasmodic, lactogage and carminative ingredient. | Tabarsa, et al. (2020)18 |
Iran | Cumin seed (zire in Iran) | Treatment of mild digestive disorders as a carminative, eupeptic, astringent in bronchopulmonary disorders, cough remedy, as well as an analgesic. | Minooeianhaghighi, Sepehrian and Shokri (2017)22 |
Iran | stimulant, carminative, coagulant, and anti-diabetic properties. | Jafari, Sattari and Ghavamzadeh (2017)1 | |
Tunisia | Seed | Aromatic herbs and culinary spices, stimulant, carminative, astringent, and as a remedy against indigestion, flatulence, and diarrhea. | Rebey et al. (2017)6 |
Italy | Seeds | Aromatic herbs for toothaches, gastrointestinal, and neurological diseases. | Benelli et al. (2018)21. |
Morocco | Seeds | Flavoring of foods especially soft dates. | Petretto et al. (2018)10. |
Phytochemistry of Cumin
The various parts of the cumin plant (leaves, shoot, root, and flowers) contain similar and different chemical compounds13. The most important chemicals which have been identified from cumin essential oils are shown in Table 2.
Compound | Chemical category | Part/Extract | References |
Cumin aldehyde | Essential oil | Seed and fruit | Kedia et al. (2015)19; Moghaddam et al. (2015)14; Jafari, Sattari and Ghavamzadeh (2017)1; Petretto et al. (2018)10. |
γ-Terpinine | Essential oil | Seed and fruit | Naeini, Naderi, and Shokri, (2014)23; Kedia et al. (2015)19; Moghaddam et al. (2015)14; Jafari, Sattari and Ghavamzadeh (2017)1. |
α-Sabinin | Essential oil | Seed | Jafari, Sattari and Ghavamzadeh (2017)1. |
α-Flandren | Essential oil | Seed | Jafari, Sattari and Ghavamzadeh (2017)1. |
α-Kadinin | Essential oil | Seed | Jafari, Sattari and Ghavamzadeh (2017)1. |
p-Cymene | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23; Kedia et al. (2015)19; Moghaddam et al. (2015)14; Petretto et al. (2018)10 |
α-Pinene | Essential oil | Fruit | Naeini, Naderi, and Shokri, (2014)23; Moghaddam et al. (2015)14; Petretto et al. (2018)10 |
(−)-β-Pinene | Essential oil | Seed | Kedia et al. (2015)19; Petretto et al. (2018)10 |
α-Phellandrene, | Essential oil | Fruit | Moghaddam et al. (2015)14; Petretto et al. (2018)10; |
α-Terpinene | Essential oil | Fruit | Moghaddam et al. (2015)14; Petretto et al. (2018)10 |
α-Terpineol | Essential oil | Fruit | Naeini, Naderi, and Shokri, (2014)23; Moghaddam et al. (2015)14; Petretto et al. (2018)10 |
Safranal | Essential oil | Fruit | Moghaddam et al. (2015)14; |
Limonene | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23; Petretto et al. (2018)10. |
1,8-Cineole | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23; Petretto et al. (2018)10. |
Linalool | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23;. |
Linalyl acetate | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23;. |
α-Terpineol acetate | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23;. |
Geraniol | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23;. |
Methyl eugenol | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23;. |
Sabinene | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23; Petretto et al. (2018)10. |
Terpinolene | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23; Petretto et al. (2018)10. |
α-Thujene | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23; Petretto et al. (2018)10. |
Myrcene | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23; Petretto et al. (2018)10. |
γ-Terpineol | Essential oil | Seed | Naeini, Naderi, and Shokri, (2014)23; Petretto et al. (2018)10. |
Daucene | Essential oil | Seed | Petretto et al. (2018)10 |
d3-Carene | Essential oil | Seed | Petretto et al. (2018)10 |
Pinocarvone | Essential oil | Seed | Petretto et al. (2018)10 |
Cariophyllene | Essential oil | Seed | Petretto et al. (2018)10 |
Farnesene-(Z)-β | Essential oil | Seed | Petretto et al. (2018)10 |
Germacrene D | Essential oil | Seed | Petretto et al. (2018)10 |
α-Acoradiene | Essential oil | Seed | Petretto et al. (2018)10 |
Carotol | Essential oil | Seed | Petretto et al. (2018)10 |
Biological activities of Cumin
The most important biological activities of cumin found in literature are summarized in Table 3. They include antioxidant, antibacterial, antifungal, anti-inflammatory, antidiabetic, insecticide, and immunomodulatory properties.
Properties | Model | Findings | References |
Antioxidant | In vitro | The antioxidant activities of cumin essential oils are positively correlated with their phenolic contents which increase at stages of intermediate and premature. | Moghaddam et al. (2015)14; Mohamed, Hamed and Fouda (2018)26. |
Antibacterial | In vitro | Ethanolic extracts of C. cyminum antibacterial effect have against Staphylococcus aureus. | Mostafa et al. (2018)28. |
Antifungal | In vitro | C. cyminum essential oils have a broad-spectrum antifungal effect against several pathogenic Candida species | Naeini, Naderi, and Shokri (2014)23; Minooeianhaghighi, Sepehrian and Shokri, (2017)22; Petretto et al. (2018)10. |
Anti-inflammatory | Animal model (rat) | Nine weeks of intervention improved plasma nitric oxide, decreased the systolic blood pressure up-regulated the gene expression of eNOS, Bcl-2, TRX1, and TRXR1; and down-regulated Bax, TNF-α, and IL-6. | Kalaivani, Saranya and Ramakrishnan (2013)24; Srinivasan (2018)27. |
Antidiabetic and anti-inflammatory | Human | Eight weeks of intervention improved fasting blood glucose, glycosylated hemoglobin as well as serum levels of insulin, TNF-α, C-reactive protein, and adiponectin. | Jafari, Sattari and Ghavamzadeh, (2017)1 |
Insecticide | Insect vectors | Cumin essential oils were very active against adults of Musca persicae (LC50=3.2 ml/L) and M. domestica (LD50=31.8 μg/adult). | Benelli et al. (2018)21. |
Immunomodulatory | Animal (Swiss albino mice) | Cumin administration significantly increased CD4 and CD8 (T cells) count through the modulation of T lymphocytes expression and dose-dependently. | Chauhan et al. (2010)25; Srinivasan (2018)27; Tabarsa et al. (2020)18. |
Antioxidant activity
Cumin essential oils have remarkable antioxidant activities and phenolic contents which increase with maturity14. Both the pure extracts and active agents of the European cumin have also been evaluated and found to be highly effective29. Mohamed, Hamed and Fouda (2018)24 have reported that cumin extract contains 23.02 ± 0.045 mg GAE/g extract and 19 ± 0.132 mg QE/g extract for total phenolic and total flavonoids, respectively.
Antimicrobial activity
The antibacterial activity of ethanolic extracts of C. cyminum against Staphylococcus aureus has been reported25. The essential oils of C. cyminum also possess antimicrobial properties30. Coronatine elicitation reportedly enhanced the yield and level of chemical components, as well as antibacterial, antifungal, antioxidant and in vitro cytotoxic activities of the cumin essential oil31. The antifungal effects of C. cyminum essential oils against Candida albicans have also been reported22. According to literature, cumin has demonstrated a broad-spectrum antifungal effect against several pathogenic Candida and other fungal species23, 10.
Antidiabetic activity
The supplementation of C. cyminum has reportedly improved fasting blood glucose level and glycosylated hemoglobin readings1. C. cyminum essential oil was also reported to exhibit maximum antidiabetic inhibition activity of α-amylase32.
Anti-inflammatory activity
According to literature, treatments supplemented with C. cyminum have a profound effect on several inflammatory biomarkers, such as adiponectin, high-sensitivity C-reactive protein (hsCRP), and TNF-α 26, 1. Srinivasan (2018)27 has also reported a detailed anti-inflammatory activity of C. cyminum.
Insecticide activity
Cumin essential oils possess effective insecticide activity against adult Myzus persicae and Musca domestica21.
Immunomodulatory activity
Cumin is an effective immunomodulatory agent whose administration significantly and dose-dependently increased the CD4+ and CD8+ T cell count and modulated T lymphocyte expression28. The detailed immunomodulatory and other beneficial properties of C. cyminum have also been reported in literature 27, 18.
Conclusion
Cumin is mostly cultivated for its numerous medicinal, nutraceutical, and pharmaceutical properties. It also has a wide use in beverage, food, liquor, medicine, perfume, and toiletry. The medicinal and health potentials of cumin are mainly attributed to its antioxidant, antibacterial, antifungal, anti-inflammatory, antidiabetic, insecticide, and immunomodulatory properties. The various parts of the cumin plant (leaves, shoot, root, and flowers) also contain similar and different chemical compounds. More studies are, however, required to unravel novel components and applications of cumin.
Abbreviations
eNOS: Endothelial nitric oxide synthase,
hsCRP: high-sensitivity C-reactive protein
IL-6: Interleukin-6
TNF-α: Tumor necrosis factor-alpha
TRX1: Thioredoxin 1
TRXR1: Thioredoxin reductase 1
Acknowledgments
The authors greatly acknowledge the technical support from the Department of Biology, Faculty of Applied Sciences, Universiti Teknologi MARA, 40450, Shah Alam, Selangor, Malaysia.
Author’s contributions
Abdulmutalib Alabeed Allaq, Norrizah Jaafar Sidik, Aziyah Abdul-Aziz, and Idris Adewale Ahmed were all involved in the review conceptualization and first draft of the manuscript. Then All authors were involved in the first review and subsequent completion of the review. And all the authors were then involved in the critical review of the manuscript, final review, and editing. All authors read and approved the final manuscript.
Funding
Not applicable.
Availability of data and materials
Not applicable.
Ethics approval and consent to participate
Not applicable.
Consent for publication
Not applicable.
Competing interests
The authors declare that they have no competing interests.
References
-
Jafari
S.,
Sattari
R.,
Ghavamzadeh
S.,
Evaluation of the effect of 50 and 100 mg doses of Cuminum cyminum essential oil on glycemic indices, insulin resistance and serum inflammatory factors on patients with diabetes type II: A double-blind randomized placebo-controlled clinical trial. Journal of Traditional and Complementary Medicine.
2017;
7
(3)
:
332-338
.
View Article PubMed Google Scholar -
Ahmed
I.A.,
Mikail
M.A.,
Ibrahim
M.,
Hazali
N.,
Antioxidant activity and phenolic profile of various morphological parts of underutilised Baccaurea angulata fruit. Food Chemistry.
2015;
172
:
778-787
.
View Article PubMed Google Scholar -
Ibrahim
M.,
Ahmed
I.A.,
Mikail
M.A.,
Ishola
A.A.,
Draman
S.,
Isa
M.L.,
Yusof
A.M.,
Baccaurea angulata fruit juice reduces atherosclerotic lesions in diet-induced Hypercholesterolemic rabbits. Lipids in Health and Disease.
2017;
16
(134)
:
1-8
.
View Article PubMed Google Scholar -
Ahmed
I.A.,
Mikail
M.A.,
Mustafa
M.R.,
Ibrahim
M.,
Othman
R.,
Lifestyle Interventions for Nonalcoholic Fatty Liver Disease. Saudi Journal of Biological Sciences.
2019;
26
:
1519-1524
.
View Article PubMed Google Scholar -
Ahmed
I.A.,
Mikail
M.A.,
Zamakshshari
N.,
Abdullah
A.H.,
Natural Anti-aging Skincare: Role and Potential. Biogerontology.
2020;
21
:
293-310
.
View Article PubMed Google Scholar -
Rebey
I.B.,
Relation between salt tolerance and biochemical changes in cumin (Cuminum cyminum L.) seeds. Journal of Food and Drug Analysis.
2017;
25
(2)
:
391-402
.
View Article PubMed Google Scholar -
Bhatt
J.,
Kumar
S.,
Patel
S.,
Solanki
R.,
Sequence-related amplified polymorphism (SRAP) markers based genetic diversity analysis of cumin genotypes. Annals of Agrarian Science.
2017;
15
(4)
:
434-438
.
View Article Google Scholar -
Kanani
P.,
Shukla
Y.M.,
Modi
A.R.,
Subhash
N.,
Kumar
S.,
Standardization of an efficient protocol for isolation of RNA from Cuminum cyminum. Journal of King Saud University - Science.
2019;
31
(4)
:
1202-1207
.
View Article Google Scholar -
Thippeswamy
N.,
Naidu
K.A.,
Antioxidant potency of cumin varieties-cumin, black cumin and bitter cumin-on antioxidant systems. European Food Research and Technology.
2005;
220
(5-6)
:
472-476
.
View Article Google Scholar -
Petretto
G.L.,
Fancello
F.,
Chemical composition and antimicrobial activity of essential oils from Cuminum cyminum L. collected in different areas of Morocco. Food Bioscience.
2018;
22
:
50-58
.
View Article Google Scholar -
Piri
R.,
Moradi
A.,
Balouchi
H.,
Salehi
A.,
Improvement of cumin (Cuminum cyminum) seed performance under drought stress by seed coating and biopriming. Scientia Horticulturae.
2019;
257
:
108667
.
View Article Google Scholar -
Soltani
E.,
Mortazavian
S.M.M.,
Non-deep simple morphophysiological dormancy in seeds of Cuminum cyminum L. Journal of Applied Research on Medicinal and Aromatic Plants.
2019;
15
:
100222
.
View Article Google Scholar -
Ghannadnia
M.,
Haddad
R.,
Zarinkamar
F.,
Sharifi
M.,
Manganese treatment effects on terpene compounds of Cuminum cyminum flowers. Industrial Crops and Products.
2014;
53
:
65-70
.
View Article Google Scholar -
Moghaddam
M.,
Miran
S.N.K.,
Pirbalouti
A.G.,
Mehdizadeh
L.,
Ghaderi
Y.,
Variation in essential oil composition and antioxidant activity of cumin (Cuminum cyminum L.) fruits during stages of maturity. Industrial Crops and Products.
2015;
70
:
163-169
.
View Article Google Scholar -
Rostami
H.,
Development of cumin essential oil nanoemulsions and its emulsion filled hydrogels. Food Bioscience.
2018;
26
(2018)
:
126-132
.
View Article Google Scholar -
Zhao
Y.,
Three-stage microwave extraction of cumin (Cuminum cyminum L.) Seed essential oil with natural deep eutectic solvents. Industrial Crops and Products.
2019;
140
(2019)
:
111660
.
View Article Google Scholar -
Milan
K.S.M.,
Dholakia
H.,
Tiku
P.K.,
Vishveshwaraiah
P.,
Enhancement of digestive enzymatic activity by cumin (Cuminum cyminum L.) and role of spent cumin as a bionutrient. Food Chemistry.
2008;
110
(3)
:
678-683
.
View Article Google Scholar -
Tabarsa
M.,
Isolation, structural elucidation and immuno-stimulatory properties of polysaccharides from Cuminum cyminum. Carbohydrate Polymers.
2020;
230
:
115636
.
View Article PubMed Google Scholar -
Kedia
A.,
Prakash
B.,
Mishra
P.K.,
Dwivedy
A.K.,
Dubey
N.K.,
Biological activities of Cuminum cyminum seed oil and its major components against Callosobruchus chinensis and Sitophilus oryzae. Journal of Asia-Pacific Entomology.
2015;
18
(3)
:
383-388
.
View Article Google Scholar -
Packiavathy
I.A.S.V.,
Antibiofilm and quorum sensing inhibitory potential of Cuminum cyminum and its secondary metabolite methyl eugenol against Gram negative bacterial pathogens. Food Research International.
2012;
45
(1)
:
85-92
.
View Article Google Scholar -
Benelli
G.,
Pavela
R.,
Not just popular spices! Essential oils from Cuminum cyminum and Pimpinella anisum are toxic to insect pests and vectors without affecting non-target invertebrates. Industrial Crops & Products.
2018;
124
(2018)
:
236-243
.
View Article Google Scholar -
Minooeianhaghighi
M.H.,
Shokri
H.,
Antifungal effects of Lavandula binaludensis and Cuminum cyminum essential oils against Candida albicans strains isolated from patients with recurrent vulvovaginal candidiasis. Journal de Mycologie Médicale.
2017;
27
(1)
:
65-71
.
View Article PubMed Google Scholar -
Naeini
A.,
Naderi
N.J.,
Shokri
H.,
Analysis and in vitro anti-Candida antifungal activity of Cuminum cyminum and Salvadora persica herbs extracts against pathogenic Candida strains. Journal de Mycologie Médicale.
2014;
24
:
13-18
.
View Article PubMed Google Scholar -
Kalaivani
P.,
Saranya
R.B.,
Ramakrishnan
G.,
Cuminum cyminum, a dietary spice, attenuates hypertension via endothelial nitric oxide synthase and NO pathway in renovascular hypertensive rats. Clinical and Experimental Hypertension.
2013;
35
(7)
:
534-542
.
View Article PubMed Google Scholar -
Chauhan
P.S.,
Satti
N.K.,
Suri
K.A.,
Amina
M.,
Bani
S.,
Stimulatory effects of Cuminum cyminum and flavonoid glycoside on Cyclosporine-A and restraint stress-induced immune-suppression in Swiss albino mice. Chemico-Biological Interactions.
2010;
185
:
66-72
.
View Article PubMed Google Scholar -
Mohamed
D.A.,
Hamed
I.M.,
Fouda
K.A.,
Antioxidant and Anti-diabetic Effects of Cumin Seeds Crude Ethanol Extract. Journal of Biological Sciences.
2018;
18
:
251-259
.
View Article Google Scholar -
Srinivasan
K.,
Cumin (Cuminum cyminum) and black cumin (Nigella sativa) seeds: traditional uses, chemical constituents, and nutraceutical effects. Food Quality and Safety.
2018;
2
(1)
:
1-16
.
View Article Google Scholar -
Mostafa
A.A.,
Antimicrobial activity of some plant extracts against bacterial strains causing food poisoning diseases. Saudi Journal of Biological Sciences.
2018;
25
(2)
:
361-366
.
View Article PubMed Google Scholar -
Akrami
F.,
Rodríguez-Lafuente
A.,
Bentayeb
K.,
Antioxidant and antimicrobial active paper based on Zataria (Zataria multiflora) and two cumin cultivars (Cuminum cyminum). LWT - Food Science and Technology.
2015;
60
(2)
:
929-933
.
View Article Google Scholar -
Khalil
N.,
Ashour
M.,
Fikry
S.,
Singab
A.N.,
Salama
O.,
Chemical composition and antimicrobial activity of the essential oils of selected Apiaceous fruits. Future Journal of Pharmaceutical Sciences.
2018;
4
(1)
:
88-92
.
View Article Google Scholar -
Taghizadeh
S.F.,
Coronatine elicitation alters chemical composition and biological properties of cumin seed essential oil. Microbial Pathogenesis.
2019;
130
:
253-258
.
View Article PubMed Google Scholar -
Tahir
H.U.,
Chemical Composition and Antidiabetic Activity of Essential Oils Obtained from Two Spices (Syzygium aromaticum and Cuminum cyminum). International Journal of Food Properties.
2016;
19
(10)
:
2156-2164
.
View Article Google Scholar
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Volume & Issue : Vol 7 No 9 (2020)
Page No.: 4016-4021
Published on: 2020-09-30
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