Biomedical Research and Therapy Biomedical Research and Therapy http://www.bmrat.org/ Biomedical Research and Therapy Biomedpress 2198-4093 Prevalence of blood pressure among students in Jiangsu Province, China Musa Taha Hussein taha.hm99@yahoo.com (THM) 1 2 Li Wei 1 Ahmad Tauseef 1 Jinjin Chu 1 Musa Hassan Hussein 3 Wei Pingmin mpw1963@126.com (PW) 1 Key Laboratory of Environmental Medicine Engineering, Ministry of Education; Department Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, 210009, Jiangsu Province, China Biomedical Research Institute, Darfur University College Nyala, Sudan Faculty of Medical Laboratory Sciences, University of Khartoum Khartoum, Sudan 31 8 2019 Copyright 2019 Abstract

Aim: Obesity and Blood Pressure (BP) is a serious public health issue. The study aims to assess the prevalence of BP and the factors associated with High Blood Pressure (HBP) among student in Jiangsu Province, China. Methods: A cross-sectional epidemiological study. A total of 101886 students (62,065 boys and 39,821 girls) aged range from 7-22 yea rs were recruited in 2010-2013. Anthropometric measurements and BP prevalence were measured, and in addition, body mass index (BMI) was calculated. We assess the prevalence of BP according to the National Blood Pressure Reference for Chinese Han children and adolescents. Results: A significant difference was observed in HBP prevalence in terms of student gender, region, age and BMI (P<0,001). Overweight and obesity were significantly associated with HBP (P<0.001). Conclusions: The findings convey an important message to the parents, health institutions that urgent action is needed to enhance effective control of HBP among the overweight and obese, and among those are living in a rural area.

Keywords Blood Pressure (BP) Jiangsu Province Student Body Mass Index (BMI) Introduction

Obesity is a global health problem1. The prevalence was significantly increased in all countries1,2,3. Approximately 2.8 million people were dying each year because of overweight4. Body Mass Index (BMI) was commonly used for screening overweight and obese in clinical practice and population survey5. High blood pressure (hypertension) was significantly increased among Chinese recently6. Obesity is a risk factor for diabetes, stroke, cardiovascular diseases and their complications6,7. Ten million persons in the world die annually with BP6. Childhood BP is a significant predictor of adulthood BP8. Development of socio-economic in China results in massively increased health issues2,3,6.

The trend of BP prevalence was reported among Chinese children and adolescents3,6,9,10,11,12,13,14. However, little is known about their association with gender, age, region and BMI level among student in Jiangsu Province. The province, is located in eastern-central coastal of China, covered 102,600 km2 and total population 80,400,000 in 2018 (https://en.wikipedia.org/wiki/Jiangsu). The data was obtained from the Students Physical Fitness and Health Surveys (SPFHS), conducted from 2010 to 2013. The aim was to assess the prevalence of HBP and NBP among students.

<bold id="s-aa21c466202d">A): Blood pressure prevalence based gender; B): Region wise distribution, C): Age wise distribution, D): BMI wise distribution; Gender, region, age and BMI differences P<0.001</bold>

<bold id="s-ee2951933ad7">Association between Blood Pressure and study variables</bold>
Variables S.E. P-value OR (95.0% C.I.)
Gender (Male/Female) 0.05 0.001 0.77 (0.69-0.85)
Region (Urban/Rural) 0.05 0.001 1.19 (1.09-1.31)
Age in years (7-11) 0.001 Reference
12-14 0.07 0.001 2.21 (1.91-2.56)
15-17 0.07 0.001 2.42 (2.09-2.80)
18-22 5.40 0.001 0.83 (0.77-0.90)
BMI (Normal weight) 0.001 Reference
Overweight 0.06 0.001 1.27 (1.12-1.44)
Obesity 0.06 0.001 2.44 (2.15-2.75)
Constant 0.13 0.001 0.017

Methods

A cross-sectional study was carried out during September 2010 to September 2013. The study subjects includes male and female students aged 7-22 years enrolled in Students Physical Fitness and Health Surveys (SPFHS). The study population were randomly selected from 10 universities and 82 schools in Jiangsu Province, resulting in an estimated sample of, 101,886 students (62,065 boys and 39,821 girls). Data were collected by trained health staff and physician from Jiangsu Center for Disease Prevention and Control (CDC) health team.

Students BP was assessed using a portable digital monitors Omron HEM 705 CP (OMRON, Kyoto, Japan), and blood pressure was measured on the right arm twice, in the morning and, no less than 30 minutes after breakfast, when children had empty bladders, after at least 5 minutes of rest, sitting, with back support and feet on the ground, without moving or talking12.

Normal Blood Pressure (NBP) was defined as anyone with Systolic Blood Pressure 120 -129 (mmHg), and Diastolic Blood Pressure is <80 (mmHg). High Normal Blood Pressure for anyone with Systolic Blood Pressure 130-139 (mmHg) or Diastolic Blood Pressure is 80-89 (mmHg). The average value of three BP readings was recorded. HBP and NBP prevalence were evaluated using new CCBP reference13, and update of the age and gender-specific BP cutoffs for Chinese children and adolescents reference15. Student body Mass Index (BMI)2 was calculated from height and weight. BMI cut-off recommended by Working Group on Obesity in China16. The study protocol was approved by the Institutional review board of School of public health Southeast University, Nanjing. A written informed consent was obtained from each participant’s parent for those in primary school. A total of 101,886 students were agreed to complete anthropometric measurement. All analyses were performed using SPSS version 25.0 for Windows (IBM SPSS, Chicago, IL, USA).

Results and Discussion

There was a significant difference in the prevalence of BP between gender, region, age groups and BMI categories, respectively (P<0.001). BMI level had a higher BP among overweight and obese groups (Figure 1). BP was significantly (P<0.001) associated with the rural area, age 12-14, age 15-17, and BMI level, including overweight, and obese group (Table 1)

The study confirmed that obesity could lead to serious health problems,2,7,8 there was a significant difference in BP prevalence within the overweight and obese groups compared with the normal weight15 and the finding is line with previous studies2,3,7. Age, region and BMI level were significantly associated with the risk of HBP, similar to study reported in China6.

In conclusions, the prevalence of BP was recorded high in females as compared to males. Results suggest that high BP is attributed mainly to a residential area (urban vs. rural), age groups and BMI level (Overweight and obese). Nevertheless, the risk of overweight and obesity are considered the significant risk factor associated with BP rate. In a public health point of view, early action is needed to reduce blood pressure and to control the factors related to high BP towards student health in the future.

Abbreviations

BP: Blood Pressure

BMI: Body Mass Index

HBP: High Blood Pressure

NBP: Normal Blood Pressure

SPFHS: Students Physical Fitness and Health Surveys

Authors' Contributions

Idea and study designed: THM

Funding

The study was funded by Jiangsu Provincial Social Science Foundation, grant number 13TYA001.

Acknowledgement

The authors thank P.W and the staff of Jiangsu Health Literacy Promotion and Research Office for providing access to the student health data for analysis.

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