<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Archiving and Interchange DTD v1.1d1 20130915//EN" "JATS-archivearticle1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="letter" dtd-version="1.1d1"><front><journal-meta><journal-title-group><journal-title>Biomedical Research and Therapy</journal-title></journal-title-group><issn pub-type="epub" publication-format="electronic">2198-4093</issn><publisher><publisher-name>BioMedPress</publisher-name></publisher></journal-meta>
<article-meta><article-id pub-id-type="doi">10.15419/bmrat.v4i12.390</article-id><article-categories><subj-group subj-group-type="display-channel"><subject>Letter</subject></subj-group><subj-group subj-group-type="heading"><subject>Biomedical Research and Therapy</subject></subj-group></article-categories><title-group><article-title>Role of socioeconomic disparities in incidence and mortality of chronic kidney disease</article-title></title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Mohammadian</surname><given-names>Mahdi</given-names></name>
<xref ref-type="aff" rid="aff1" />
<xref ref-type="aff" rid="aff2" />
</contrib>
<contrib contrib-type="author"><name><surname>Salehiniya</surname><given-names>Hamid</given-names></name>
<xref ref-type="aff" rid="aff3" />
</contrib>
<contrib contrib-type="author"><name><surname>Allah Bakeshei</surname><given-names>Fatemeh</given-names></name>
<xref ref-type="aff" rid="aff4" />
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Mohammadian-Hafshejani</surname><given-names>Abdollah</given-names></name>
<xref ref-type="aff" rid="aff5" />
<xref ref-type="aff" rid="aff6" /><xref ref-type="corresp" rid="cor1">*</xref>
</contrib>
<aff id="aff1"><institution>Department of Social Medicine, School of Public Health, Dezful University of Medical Sciences, Dezful, Iran</institution></aff>
<aff id="aff2"><institution>Researcher, School of Public Health, Iran University of Medical Sciences, Tehran, Iran</institution></aff>
<aff id="aff3"><institution>Zabol University of Medical Sciences, Zabol, Iran</institution></aff>
<aff id="aff4"><institution>PhD Candidate, Social Determinants of Health Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran</institution></aff>
<aff id="aff5"><institution>Department of Epidemiology and Biostatistics, School of Public Health,  Shahrekord University of Medical Sciences, Shahrekord, Iran</institution></aff>
<aff id="aff6"><institution>Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran</institution></aff>
</contrib-group>
<author-notes><corresp id="cor1"><label>*</label>For correspondence: <email>amohamadii1361@gmail.com</email></corresp><fn fn-type="con" id="equal-contrib"><label>*</label><p>These authors contributed equally to this work</p></fn></author-notes>
<pub-date date-type="pub" publication-format="electronic"><day>18</day><month>12</month><year>2017</year></pub-date>
<volume>4</volume>
<issue>12</issue>
<fpage>1</fpage>
<lpage>8</lpage>
<history><date date-type="received"><day>19</day><month>10</month><year>2017</year></date>
<date date-type="accepted"><day>07</day><month>11</month><year>2017</year></date></history>
<permissions><copyright-statement>Copyright: &#x000a9; The Author(s) 2017</copyright-statement><copyright-year>2017</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/CC-BY/4.0"><license-p>This article is published with open access by BioMedPress (BMP), Laboratory of Stem Cell Research and Application, Vietnam National University, Ho Chi Minh city, Vietnam This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.</license-p></license></permissions>
<self-uri content-type="pdf" xlink:href="http://www.bmrat.org/index.php/BMRAT/article/view/390/789"/>
<abstract>
<p>Chronic kidney disease (CKD) is a public health problem known as one of the most important factors for premature death <xref ref-type="bibr" rid="ref2">Coresh et al., 2007</xref><xref ref-type="bibr" rid="ref6">Martins et al., 2012</xref>. The disparity in the distribution of CKD is due to the socio-economic factors, gender, ethnicity and race at the global level <xref ref-type="bibr" rid="ref8">Norris and Nissenson, 2008</xref><xref ref-type="bibr" rid="ref9">Norris and Agodoa, 2005</xref>. Roles of socio-economic conditions have been recently taken into account as a key factor in the pathway of CKD creation and expansion <xref ref-type="bibr" rid="ref1">Bruce et al., 2009</xref><xref ref-type="bibr" rid="ref7">Nicholas et al., 2015</xref>. Several studies worldwide investigated a strong relationship between socioeconomic status and incidence of CKD complications <xref ref-type="bibr" rid="ref3">Crews et al., 2012</xref><xref ref-type="bibr" rid="ref4">Jurkovitz et al., 2012</xref><xref ref-type="bibr" rid="ref10">Saab et al., 2012</xref>.</p>
</abstract>
<kwd-group>
<kwd>Chronic kidney disease</kwd>
<kwd>End-stage renal disease</kwd>
<kwd>Poverty</kwd>
<kwd>Socioeconomics</kwd>
</kwd-group></article-meta></front>
<body>
<sec id="s1">
<title>Dear Editor-in-Chief</title>
<p>Chronic kidney disease (CKD) is a public health problem known as one of the most important factors for premature death <xref ref-type="bibr" rid="ref2">Coresh et al., 2007</xref><xref ref-type="bibr" rid="ref6">Martins et al., 2012</xref>. The disparity in the distribution of CKD is due to the socio-economic factors, gender, ethnicity and race at the global level <xref ref-type="bibr" rid="ref8">Norris and Nissenson, 2008</xref><xref ref-type="bibr" rid="ref9">Norris and Agodoa, 2005</xref>. Roles of socio-economic conditions have been recently taken into account as a key factor in the pathway of CKD creation and expansion <xref ref-type="bibr" rid="ref1">Bruce et al., 2009</xref><xref ref-type="bibr" rid="ref7">Nicholas et al., 2015</xref>. Several studies worldwide investigated a strong relationship between socioeconomic status and incidence of CKD complications <xref ref-type="bibr" rid="ref3">Crews et al., 2012</xref><xref ref-type="bibr" rid="ref4">Jurkovitz et al., 2012</xref><xref ref-type="bibr" rid="ref10">Saab et al., 2012</xref>. Martins et al. studied the relationship between microalbuminuria and macroalbuminuria and the individual economic and social situation in the United States of America, so that the odds ratio of microalbuminuria in the poor (defined as less than 200% federal poverty level) was equal to 1.35; 95% confidence interval (CI): 1.22-1.49 and for macroalbuminuria was equal to 1.78; 95% CI: 1.40- 2.26 compared to other people. According to another study by Lipworth et al., the risk of end-stage renal disease (ESRD) in people with the income level of less than or equal to $15000 per year was 50% more than others <xref ref-type="bibr" rid="ref5">Lipworth et al., 2012</xref>. Risk of ESRD incidence in homeless people was also more than those who lived in houses. According to a research by Jurkovitz et al on people aged 65 and under at the high risk of CKD (people with diabetes or hypertension, and also those with a family history of CKD), the probability of ESRD incidence in the poor without insurance was 72% higher than the poor with insurance <xref ref-type="bibr" rid="ref4">Jurkovitz et al., 2012</xref>. Therefore, the lack of health insurance, which is more prevalent among the poor, is, in fact, a risk factor for incidence of ESRD among people at the high risk of disease. Consequently, it is suggested paying attention to people at lower social and economic classes, homeless people and those without health insurance in case finding and screening programs. Health policy makers should also pay attention to roles of social and economic factors in the prevention of incidence and reduction of complications and mortality due to the kidney diseases. Appropriate measures should also be taken to put the poor under the health insurance coverage to reduce the incidence and mortality of kidney diseases.</p>
</sec>
<sec id="s2">
<title>Abbreviations</title>
<p>CI: Confidence Interval</p>
<p>CKD: Chronic kidney disease</p>
<p>ESRD: End Stage Renal Disease</p>
</sec>
</body>
<back>
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