<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Archiving and Interchange DTD v1.1d1 20130915//EN" "JATS-archivearticle1.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="case-report" dtd-version="1.1d1">
  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>Biomedical Research and Therapy</journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2198-4093</issn>
      <publisher>
        <publisher-name>BioMedPress</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.15419/bmrat.v4i07.196</article-id>
      <article-categories>
        <subj-group subj-group-type="display-channel">
          <subject>Case Report</subject>
        </subj-group>
        <subj-group subj-group-type="heading">
          <subject>Biomedical Research and Therapy</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Inequality in Human Development Index and suicide death in Iran: A National Register&#8211;Based Study</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Veisani</surname>
            <given-names>Yousef</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Delpisheh</surname>
            <given-names>Ali</given-names>
          </name>
          <xref ref-type="aff" rid="aff2"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Mohamadian</surname>
            <given-names>Fathola</given-names>
          </name>
          <xref ref-type="aff" rid="aff3"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Baghri</surname>
            <given-names>Maryam</given-names>
          </name>
          <xref ref-type="aff" rid="aff4"/>
        </contrib>
        <contrib contrib-type="author" corresp="yes">
          <name>
            <surname>Khazaei</surname>
            <given-names>Salman</given-names>
          </name>
          <xref ref-type="aff" rid="aff5"/>
          <xref ref-type="corresp" rid="cor1">*</xref>
        </contrib>
        <aff id="aff1">
          <institution>Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran</institution>
        </aff>
        <aff id="aff2">
          <institution>Department of Clinical Epidemiology, Ilam University of Medical Sciences, Ilam-Iran</institution>
        </aff>
        <aff id="aff3">
          <institution>Department of Psychology, Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran</institution>
        </aff>
        <aff id="aff4">
          <institution>Department of Physiology, Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran</institution>
        </aff>
        <aff id="aff5">
          <institution>Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran</institution>
        </aff>
      </contrib-group>
      <author-notes>
        <corresp id="cor1"><label>*</label>For correspondence: <email>salman.khazaei61@gmail.com</email></corresp>
        <fn fn-type="con" id="equal-contrib">
          <label>*</label>
          <p>These authors contributed equally to this work</p>
        </fn>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic">
        <day>28</day>
        <month>07</month>
        <year>2017</year>
      </pub-date>
      <volume>4</volume>
      <issue>7</issue>
      <fpage>1</fpage>
      <lpage>4</lpage>
      <history>
        <date date-type="received">
          <day>03</day>
          <month>07</month>
          <year>2017</year>
        </date>
        <date date-type="accepted">
          <day>21</day>
          <month>07</month>
          <year>2017</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Copyright: &#169; The Author(s) 2017</copyright-statement>
        <copyright-year>2017</copyright-year>
        <license license-type="open-access" xlink:href="http://creativecommons.org/licenses/CC-BY/4.0">
          <license-p>This article is published with open access by BioMedPress (BMP), Laboratory of Stem Cell Research and Application, Vietnam National University, Ho Chi Minh city, Vietnam This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.</license-p>
        </license>
      </permissions>
      <self-uri content-type="pdf" xlink:href="http://www.bmrat.org/index.php/BMRAT/article/view/196/526"/>
      <abstract>
        <p>Pay attention to the effects of inequality in health outcomes has steadily risen during recent years. It is necessary step to achieve the goal of health for all (HFA) in the coming decades. At the moment, our knowledge about the inequality and suicide is limited. Human Development Index (HDI) is summary measures that we can demonstrate current inequalities regarded to health outcomes. We have reanalyzed the national data by Statistical Centre of Iran for HDI and Iranian Forensic Medicine Organization for suicide to explicate of inequality in suicide death in Iran. Our results showed an inverse correlation between HDI and suicide death, so that deaths from suicide was more occurred in provinces with lower HDI. Therefore, results in current study showed a positive inequality in suicide in relation with HDI in Iran. According to this, we suggested that regional studies will be conducted to detect subgroups with a high suicide risk as well as components of HDI that cause inequality.</p>
      </abstract>
      <kwd-group>
        <kwd>Human Development Index (HDI)</kwd>
        <kwd>Inequality</kwd>
        <kwd>Socioeconomic</kwd>
        <kwd>Suicide</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="s1">
      <title>Introduction</title>
      <p>Suicide is considered as an important public health problem in both developing and developed countries, which lead to more than 800,000 deaths annually <xref ref-type="bibr" rid="ref6">Noorbala AA, 1998</xref>. The effects of inequality in health have been acknowledged in developed countries <xref ref-type="bibr" rid="ref10">Veisani et al., 2017</xref>. Researchers now aimed to reducing the inequalities in the coming decades through enhance knowledge about inequality sources. The connection between socioeconomic status (SES) and suicide has been controversial. Some have found that a deprived situations increasing the risk of suicide <xref ref-type="bibr" rid="ref1">Burrows and Laflamme, 2010</xref><xref ref-type="bibr" rid="ref11">Yoder and Hoyt, 2005</xref>, while other concluded oppose it <xref ref-type="bibr" rid="ref2">Chan et al., 2009</xref>, this diversity may be due to variety in methods being used to measure SES. Human Development Index (HDI) is summary measures that can be demonstrated current inequalities and poverty in different contraries. In current study we aimed to obtain the relationship between inequality in HDI and suicide death in Iran using national data.</p>
    </sec>
    <sec id="s2">
      <title>Materials-Methods</title>
      <p>This is an ecological study on the relation of HDI and suicide death in Iran. Data obtained from Results of the Iranian Urban and Rural Household Income and Expenditure Survey in 2013 for HDI <xref ref-type="bibr" rid="ref5">Noorbala and Akhondzadeh, 2015</xref>, and the annual reports of Iranian Forensic Medicine Organization in 2012 for suicide rate <xref ref-type="bibr" rid="ref3">Kiadaliri et al., 2014</xref>. In this study, we defined inequality in the suicide death according to the HDI by using concentration index (CI) among provinces. The value of CI is between -1 to +1 and the negative value of this index is indicating that the related variable to health is more concentrated on the poor population and the positive value indicates that the related variable to health concentrated among the rich population <xref ref-type="bibr" rid="ref4">Mohammadi et al., 2003</xref>. We used the Stata software version 12 (Stata Corp, College Station, TX, USA) to perform all the analytical operations as well as Epi Info&#8482; software for drawing maps. Significant level considered less than 5%.</p>
    </sec>
    <sec id="s3">
      <title>Results</title>
      <p>As shown in <xref ref-type="fig" rid="fig1"> Figure 1 </xref>, suicide rate in Iran ranged from 2.21 to 19.53 per 100,000 populations (average rate: 5.1). Among all provinces highest rate observed in Ilam with 19.53 and lowest in Hormozgan with 2.21 per 100,000 population. In addition, slightly more than half (56.6%) provinces had a suicide rate of 3&#8211;6 per 100,000 populations. Also figure 1 shown the HDI level for all provinces, accordingly Sistan &amp; Baluchestan and Tehran had a lowest and highest rank (0.643 and 0.843), respectively. The CI is presented in <xref ref-type="fig" rid="fig2"> Figure 2 </xref>, which shows that suicide was more occurred in provinces with lower HDI. The overall CI was -0.234 (95% CI = -0.343 to -0.124). Therefore our results confirmed a positive inequality in suicide death result from HDI in Iran. A predictor graph was shown in <xref ref-type="fig" rid="fig3"> Figure 3 </xref>. It is evident that the higher HDI was associated with lower suicide death in Iran (r= -0.089, p&lt; 0.001).</p>
      <fig id="fig1">
        <label>Figure 1</label>
        <caption>
          <p>HDI level (A) and suicide rate (B) by province in 2013</p>
        </caption>
        <graphic xlink:href="bmrat.v4i07.196/fig1.png"/>
      </fig>
      <fig id="fig2">
        <label>Figure 2</label>
        <caption>
          <p>Concentration curve for relation between suicide rate and HDI level</p>
        </caption>
        <graphic xlink:href="bmrat.v4i07.196/fig2.png"/>
      </fig>
      <fig id="fig3">
        <label>Figure 3</label>
        <caption>
          <p>Predictor graph for suicide rate according HDI range</p>
        </caption>
        <graphic xlink:href="bmrat.v4i07.196/fig3.png"/>
      </fig>
    </sec>
    <sec id="s4">
      <title>Discussion</title>
      <p>Our results were showed an inverse correlation between the HDI and suicide death in Iran. It comes to mind that people in the provinces with lower HDI rank generally have lower key dimensions of human development such as have a decent standard of living, a long and healthy life and being knowledgeable. The interesting point in our study is that provinces with high rank of suicide death such as Ilam <xref ref-type="bibr" rid="ref9">Veisani et al., 2016</xref>, Kermanshah, Lorestan and Hamadan (rank first to fourth) have a lowest HDI according to figure 1. One potential explanation for this finding can be the low SES of these provinces <xref ref-type="bibr" rid="ref8">Veisani and Delpisheh, 2015</xref>. This finding is in line with previous systematic review that found, 73% of previous studies had an inverse association between education level and suicide death and as well in relation to income and suicide in 50% of them. They also indicated that 94% of studies that preformed in Asia reign had a significant negative relationship between social rank and suicide death <xref ref-type="bibr" rid="ref7">Pearce et al., 2007</xref>.</p>
    </sec>
    <sec id="s5">
      <title>Conclusion</title>
      <p>In summary, the present study indicated that a positive inequality in suicide death rate relation to HDI in Iran. According to this important finding more studies are needed to explore the origin of inequality in local area to design and apply of intervention programs in provinces especially with high prevalence rate of suicide.</p>
    </sec>
    <sec id="s6">
      <title>Abbreviations</title>
      <p>Human Development Index (HDI)</p>
      <p>Socioeconomic status (SES)</p>
      <p>Concentration index (CI)</p>
    </sec>
    <sec id="s7">
      <title>Author contribution</title>
      <p>All authors contributed in manuscript preparation. Veisani,Y and Khazaei,S obtained data and analyzed it. Delpisheh,A and Baghri,M interpreted of data analysis. Mohamadian,F designed of figures. All authors drafted the first version and approve the final draft.</p>
    </sec>
  </body>
  <back>
    <ref-list>
      <title>References</title>
      <ref id="ref1">
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>S.</surname>
              <given-names>Burrows</given-names>
            </name>
            <name>
              <surname>L.</surname>
              <given-names>Laflamme</given-names>
            </name>
          </person-group>
          <article-title>Socioeconomic disparities and attempted suicide: state of knowledge and implications for research and prevention</article-title>
          <source>International journal of injury control and safety promotion</source>
          <year>2010</year>
          <volume>17</volume>
          <fpage>23</fpage>
          <lpage>40</lpage>
        </element-citation>
      </ref>
      <ref id="ref2">
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>W.S.</surname>
              <given-names>Chan</given-names>
            </name>
            <name>
              <surname>C.K.</surname>
              <given-names>Law</given-names>
            </name>
            <name>
              <surname>K.Y.</surname>
              <given-names>Liu</given-names>
            </name>
            <name>
              <surname>P.W.</surname>
              <given-names>Wong</given-names>
            </name>
            <name>
              <surname>Y.W.</surname>
              <given-names>Law</given-names>
            </name>
            <name>
              <surname>P.S.</surname>
              <given-names>Yip</given-names>
            </name>
          </person-group>
          <article-title>Suicidality in Chinese adolescents in Hong Kong: the role of family and cultural influences</article-title>
          <source>Social psychiatry and psychiatric epidemiology</source>
          <year>2009</year>
          <volume>44</volume>
          <fpage>278</fpage>
          <lpage>284</lpage>
        </element-citation>
      </ref>
      <ref id="ref3">
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>A.A.</surname>
              <given-names>Kiadaliri</given-names>
            </name>
            <name>
              <surname>S.</surname>
              <given-names>Saadat</given-names>
            </name>
            <name>
              <surname>H.</surname>
              <given-names>Shahnavazi</given-names>
            </name>
            <name>
              <surname>H.</surname>
              <given-names>Haghparast-Bidgoli</given-names>
            </name>
          </person-group>
          <article-title>Overall, gender and social inequalities in suicide mortality in Iran, 2006-2010: a time trend province-level study</article-title>
          <source>BMJ open</source>
          <year>2014</year>
          <volume>4</volume>
          <fpage>e005227</fpage>
        </element-citation>
      </ref>
      <ref id="ref4">
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>M.</surname>
              <given-names>Mohammadi</given-names>
            </name>
            <name>
              <surname>M.</surname>
              <given-names>Rahgozar</given-names>
            </name>
            <name>
              <surname>A.</surname>
              <given-names>Bagheri Yazdi</given-names>
            </name>
            <name>
              <surname>H.</surname>
              <given-names>Naghavi</given-names>
            </name>
            <name>
              <surname>H.R.</surname>
              <given-names>Pour Etemad</given-names>
            </name>
            <name>
              <surname>H.</surname>
              <given-names>Amini</given-names>
            </name>
            <name>
              <surname>M.</surname>
              <given-names>Rostami</given-names>
            </name>
            <name>
              <surname>B.</surname>
              <given-names>Mesgarpour</given-names>
            </name>
          </person-group>
          <article-title>Epidemiological Study of Psychiatric Disorders in Tehran Province</article-title>
          <source>Iranian Journal of Psychiatry and Clinical Psychology</source>
          <year>2003</year>
          <volume>9</volume>
          <fpage>4</fpage>
          <lpage>13</lpage>
        </element-citation>
      </ref>
      <ref id="ref5">
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>A.A.</surname>
              <given-names>Noorbala</given-names>
            </name>
            <name>
              <surname>S.</surname>
              <given-names>Akhondzadeh</given-names>
            </name>
          </person-group>
          <article-title>Mental health study process into prevalence of mental disorders in iran</article-title>
          <source>Arch Iran Med</source>
          <year>2015</year>
          <volume>18</volume>
          <fpage>74</fpage>
          <lpage>75</lpage>
        </element-citation>
      </ref>
      <ref id="ref6">
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>M.K.</surname>
              <given-names>Noorbala AA</given-names>
            </name>
            <name>
              <surname>SA</surname>
              <given-names>Bagheri Yazdi</given-names>
            </name>
          </person-group>
          <article-title>The epidemiological study of psychiatric disorders in Tehran</article-title>
          <source>J Hakim</source>
          <year>1998</year>
          <volume>4</volume>
          <fpage>212</fpage>
          <lpage>223</lpage>
        </element-citation>
      </ref>
      <ref id="ref7">
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>J.</surname>
              <given-names>Pearce</given-names>
            </name>
            <name>
              <surname>R.</surname>
              <given-names>Barnett</given-names>
            </name>
            <name>
              <surname>S.</surname>
              <given-names>Collings</given-names>
            </name>
            <name>
              <surname>I.</surname>
              <given-names>Jones</given-names>
            </name>
          </person-group>
          <article-title>Did geographical inequalities in suicide among men aged 15-44 in New Zealand increase during the period 1980- 2001?</article-title>
          <source>Australian &amp; New Zealand Journal of Psychiatry</source>
          <year>2007</year>
          <volume>41</volume>
          <fpage>359</fpage>
          <lpage>365</lpage>
        </element-citation>
      </ref>
      <ref id="ref8">
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>Y.</surname>
              <given-names>Veisani</given-names>
            </name>
            <name>
              <surname>A.</surname>
              <given-names>Delpisheh</given-names>
            </name>
          </person-group>
          <article-title>Decomposing of socioeconomic inequality in mental health: a cross-sectional study into female-headed households</article-title>
          <source>Journal of research in health sciences</source>
          <year>2015</year>
          <volume>15</volume>
          <fpage>218</fpage>
          <lpage>222</lpage>
        </element-citation>
      </ref>
      <ref id="ref9">
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>Y.</surname>
              <given-names>Veisani</given-names>
            </name>
            <name>
              <surname>A.</surname>
              <given-names>Delpisheh</given-names>
            </name>
            <name>
              <surname>K.</surname>
              <given-names>Sayehmiri</given-names>
            </name>
            <name>
              <surname>G.</surname>
              <given-names>Moradi</given-names>
            </name>
            <name>
              <surname>J.</surname>
              <given-names>Hassanzadeh</given-names>
            </name>
          </person-group>
          <article-title>Suicide attempts in Ilam Province, Western Iran, 2010-2014: a time trend study</article-title>
          <source>Journal of research in health sciences</source>
          <year>2016</year>
          <volume>16</volume>
          <fpage>64</fpage>
          <lpage>67</lpage>
        </element-citation>
      </ref>
      <ref id="ref10">
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>Y.</surname>
              <given-names>Veisani</given-names>
            </name>
            <name>
              <surname>G.</surname>
              <given-names>Moradi</given-names>
            </name>
            <name>
              <surname>A.</surname>
              <given-names>Delpisheh</given-names>
            </name>
          </person-group>
          <article-title>Effects of Socio-economic Status Inequality on Health Outcomes</article-title>
          <source>Arch Iran Med</source>
          <year>2017</year>
          <volume>20</volume>
          <fpage>329</fpage>
        </element-citation>
      </ref>
      <ref id="ref11">
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>K.A.</surname>
              <given-names>Yoder</given-names>
            </name>
            <name>
              <surname>D.R.</surname>
              <given-names>Hoyt</given-names>
            </name>
          </person-group>
          <article-title>Family economic pressure and adolescent suicidal ideation: application of the family stress model</article-title>
          <source>Suicide and Life-Threatening Behavior</source>
          <year>2005</year>
          <volume>35</volume>
          <fpage>251</fpage>
          <lpage>264</lpage>
        </element-citation>
      </ref>
    </ref-list>
  </back>
</article>