TY - JOUR AU - Muhammad Abu Hashmi AU - Muhammad Khawar AU - Rimsha Naseem AU - Ali Afzal AU - Nayab Shahid AU - Muddasir Abbasi AU - Nadeem Sheikh AU - Nimra Afzal AU - Maryam Mukhtar AU - Sara Shahzaman AU - Syeda Hamid AU - Ume Habiba AU - Adil Farooq AU - Muhammad Ashraf AU - Rabia Mehmood AU - Muhammad Idnan PY - 2023/04/30 Y2 - 2024/03/29 TI - Therapeutic Potential of Microbial Metabolites: New Insights and Perspectives JF - Biomedical Research and Therapy JA - BMRAT VL - 10 IS - 4 SE - Review DO - 10.15419/bmrat.v10i4.805 UR - http://bmrat.org/index.php/BMRAT/article/view/805 AB - Microbes release important metabolites that regulate various physiological activities inside and outside of organisms. The human gastrointestinal tract is a reservoir of microbes that play important regulatory roles in modulating the immune system and numerous other physiological functions. Thus, there is substantial interest in these microbial products and their clinical significance. These microbial metabolites have shown promise as therapies for cancer, inflammation, neurological disorders, and many other diseases. Here, we discuss microbial metabolites with substantial therapeutic potential, including proteasome inhibitors, therapeutic enzymes, bacteriocins, polyamines, and flavonoids. ER -